Soft tissue tumors: Liposarcoma: Myxoid liposarcoma

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Soft Tissue Tumors: Liposarcoma: Myxoid liposarcoma

Note Sarcomas are relatively rare malignant tumours and comprise less than 10% of all cancers. Classical classifications of sarcomas are based on the site of tumour (bone or soft tissue). Soft tissue sarcoma (STS) is the collective term used for malignancies arising in muscles, fat, vessels, the peripheral nervous system and fibrous tissue. Histopathologic examination of such tumours has reveal...

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Retroperitoneal perirenal myxoid liposarcoma

Liposarcomas are neoplasms of mesodermic origin, are derived from adipose tissue and represent <1% of all malignant tumours. Primary liposarcomas of the kidney are very rare. Here, we present the cases of two patients diagnosed with retroperitoneal perirenal myxoid liposarcoma. The patients were diagnosed via imaging, which in both cases revealed a huge right retroperitoneal tumour mass compres...

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Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors.

Differentiation is a complex set of events that can be blocked by rearrangements of regulatory genes producing fusion proteins with altered properties. In the case of myxoid liposarcoma (MLS) tumors, the causative abnormality is a fusion between the CHOP transcription factor and the FUS or EWS genes. CHOP belongs to and is a negative regulator of the large CAAT/enhancer binding protein family w...

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Aggressive myxoid liposarcoma of mediastinum.

Liposarcomata most frequently originate in the interfascial plane of the thigh, or in the retroperitoneal tissues.' Primary development in the mediastinum is a rare occurrence, with less than 60 cases reported in the world literature.2 3 4 5 Histopathologically, liposarcomata are classified into four basic types: well differ entiated, myxoid, round cell and pleomorphic, and the clinical behavio...

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Myxoid liposarcoma of the broad ligament.

A patient diagnosed as having a myxoid liposarcoma of the broad ligament is presented. She was treated with surgical resection and radiation therapy and is free of disease 2 years after completing surgery.

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2011

ISSN: 1768-3262

DOI: 10.4267/2042/38162